Circulating endothelial progenitor cells and endothelial cells in moyamoya disease
نویسندگان
چکیده
منابع مشابه
Circulating Endothelial Progenitor Cells in Cerebrovascular Disease
Stroke is associated with high disability and mortality burdens worldwide, but there are few effective and widely available therapies. There is therefore a need to develop treatments that promote the repair and regeneration of ischemic brain tissue. In this regard, a population of adult stem cells-called endothelial progenitor cells (EPCs)-has been identified in peripheral blood that could prov...
متن کاملCirculating Vascular Progenitor Cells in Moyamoya Disease
Various approaches have been attempted in translational moyamoya disease research. One promising material for modeling and treating this disease is vascular progenitor cells, which can be acquired and expanded from patient peripheral blood. These cells may provide a novel experimental model and enable us to obtain insights regarding moyamoya disease pathogenesis. We briefly present the recent a...
متن کاملIncreased levels of circulating endothelial progenitor cells in patients with Moyamoya disease.
BACKGROUND AND PURPOSE Chronic cerebral ischemia leads to higher risk for strokes attributable to insufficient collateralization, resulting from inadequate capacity for arteriogenesis and angiogenesis. Patients with Moyamoya disease (MMD) have similar transient ischemic attack frequencies compared to patients with chronic cerebral ischemia with other etiologies, but a strong capacity for arteri...
متن کاملCirculating endothelial progenitor cells in malignant gliomas.
OBJECT Recent experimental work suggests that circulating endothelial progenitor cells (cEPCs) are recruited to the angiogenic vascular system of malignant gliomas. Consequently, the level of cEPCs has been proposed as a novel biomarker for the diagnosis and monitoring of these lesions. The aim of the present study was to examine the level of cEPCs and the level of EPC mobilizing mediators in t...
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How, then, are we to make progress, when experiments cannot be done in humans, and we cannot trust the results from mice? The answer is, thoughtfully. As Drs Keogh and Menache point out, genes do not work individually or in linear pathways, but rather in networks. We can use mice to work out the links in these networks, while understanding that the relative strengths of the connections are diff...
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ژورنال
عنوان ژورنال: Brain and Behavior
سال: 2018
ISSN: 2162-3279
DOI: 10.1002/brb3.1035